Causes of PCOS — Cicle Health

Despite the fact that the precise origin of the polycystic ovarian syndrome (PCOS) remains unknown, it is believed to be connected to hormone levels.

GENETICS

PCOS can run in families due to genetics. You are at a higher chance of having PCOS if any of your relatives does. Although particular genes linked to PCOS have not yet been discovered, this shows that the disorder may have a hereditary component.

INSULIN RESISTANCE

A hormone called insulin is created by the pancreas to regulate blood sugar levels. It aids in transferring blood glucose into cells, where it is broken down to create energy.

The term “insulin resistance” refers to the body’s tissues being resistant to insulin’s actions. In order to make up for this, the body must create more insulin.

High insulin levels cause the ovaries to overproduce testosterone, which interferes with the growth of follicles-the sacs in the ovaries where eggs develop-and ovulation in a healthy way.

Additionally, insulin resistance can result in weight gain, which can aggravate the symptoms of PCOS. Having additional fat encourages the body to create more insulin, so insulin resistance can also result in weight gain, which can exacerbate PCOS symptoms.

HORMONE IMBALANCE

It is discovered that many women with PCOS have an imbalance in a number of hormones, including:

increased levels of luteinizing hormone (LH) — this promotes ovulation but, if levels are too high, may have an inappropriate effect on the ovaries low levels of sex hormone-binding globulin (SHBG) — a protein in the blood that binds to testosterone and lessens its effect

There is no known cause for these hormone alterations. It’s been proposed that the issue may originate in the ovary, in other glands that make these hormones, or in the area of the brain that regulates their synthesis.